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904457

Sigma-Aldrich

Silica

monodisperse, non-porous, 1.0 μm

Synonym(s):

Monodisperse silicon dioxide, Non-porous silica, Non-porous silicon dioxide, Silica, Silicon dioxide

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About This Item

Linear Formula:
SiO2
CAS Number:
7631-86-9
Molecular Weight:
60.08
MDL number:
MFCD00011232
UNSPSC Code:
41123003
NACRES:
NA.23

form

powder

bp

2230 °C (lit.)

mp

>1600 °C (lit.)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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Application

Monodisperse nonporous silica nanoparticles find application in drug delivery and molecular imaging whereas micron sized particles are used in liquid chromatography. We offer highly monodisperse(coefficient of variance <10%) nonporous silica in size varying from 150 nm to 50 μm. The high monodispersity of our particles makes them suitable for aforementioned applications.
Silica monodispersed, non-porous (1 μm) is a micro-sized filler material can be used as a spacer in liquid crystals, high performance liquid chromatography (HPLC), and nanomedicine for biological applications.

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Practical Examination of a Nonporous Silica Stationary Phase for Reversed-Phase Fast LC Applications
D R Jenke
Journal of Chromatographic Science, 34, 362-362 (1996)
In-depth characterization of slurry packed capillary columns with 1.0-mm nonporous particles using reversed-phase isocratic ultrahigh-pressure liquid chromatography
Patel KD, et al.
Analytical Chemistry, 76(19), 5777-5786 (2004)
Size control of monodisperse nonporous silica particles by seed particle growth
Zhao B, et al.
Particuology, 9(3), 314-317 (2011)
Nonporous silica nanoparticles for nanomedicine application
Tang L and Cheng J
Nano Today, 8(3), 290-312 (2013)
Martha Kim et al.
Scientific reports, 7(1), 8238-8238 (2017-08-16)
Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of oral and ocular topical applications of 100 nm-sized SiNPs in
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