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64940

Sigma-Aldrich

N-Methoxycarbonylmaleimide

≥97.0% (N)

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About This Item

Empirical Formula (Hill Notation):
C6H5NO4
CAS Number:
Molecular Weight:
155.11
Beilstein:
1450638
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

Assay

≥97.0% (N)

form

solid

mp

63-67 °C

storage temp.

2-8°C

SMILES string

COC(=O)N1C(=O)C=CC1=O

InChI

1S/C6H5NO4/c1-11-6(10)7-4(8)2-3-5(7)9/h2-3H,1H3

InChI key

LLAZQXZGAVBLRX-UHFFFAOYSA-N

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Other Notes

For the introduction of the maleimide group in peptides, amino acids and amines

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Preparation and some properties of maleimido acids and maleoyl derivatives of peptides.
O Keller et al.
Helvetica chimica acta, 58(2), 531-541 (1975-03-12)
Susanne Kirchhof et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 217-225 (2015-08-09)
Eight-armed PEG was functionalized with furyl and maleimide groups (8armPEG20k-Fur and 8armPEG20k-Mal); degradable hydrogels were obtained by cross-linking via Diels-Alder chemistry. To increase the stability to degradation, the macromonomers were modified by introducing a hydrophobic 6-aminohexanoic acid spacer between PEG

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