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Key Documents

163716

Sigma-Aldrich

HEPES

Synonym(s):

4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid

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About This Item

UNSPSC Code:
12352200

form

chunks

solubility

water: 0.5 g/mL, clear, colorless

Application

Buffer useful in the physiological pH range.

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The Journal of Organic Chemistry, 58, 2663-2663 (1993)
Aldrichimica Acta, 16, 35-35 (1983)
Yun Ho Choi et al.
Anatomy & cell biology, 43(4), 317-324 (2011-01-27)
Alpha-lipoic acid (LA), a naturally occurring dithiol compound, is an essential cofactor in metabolic reactions involved in energy utilization. LA improves glycemic control, reduces diabetic polyneuropathies, atherosclerosis, and allergic inflammation. The effects of LA on mast cell-mediated anaphylactic reactions, however
M Vasseur et al.
The American journal of physiology, 264(1 Pt 1), C27-C31 (1993-01-01)
The fluorescence intensity of 6-methoxy-N-(3-sulfopropyl)quinolinium (SPQ) in an N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid (HEPES) 2-(N-morpholino)ethanesulfonic acid (MES)-Tris(hydroxymethyl)aminomethane buffer, pH 7.0, decreased as a function of Cl- concentration and/or gluconate concentration, as expected. Contrary to expectation, however, the fluorescence intensity progressively increased as the
Joshua A Smith et al.
Brain research, 1301, 163-170 (2009-09-15)
PTEN is a tumor suppressor gene that is either mutated or deleted in a number of human cancers. PTEN acts as a negative regulator of the PI3K/Akt survival pathway and thus plays an important role in cell fate, proliferation, growth

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