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129364

Sigma-Aldrich

4-Iodoaniline

98%

Synonym(s):

p-Iodoaniline

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About This Item

Linear Formula:
IC6H4NH2
CAS Number:
540-37-4
Molecular Weight:
219.02
Beilstein:
774101
EC Number:
208-743-4
MDL number:
MFCD00007848
UNSPSC Code:
12352100
PubChem Substance ID:
24847899
NACRES:
NA.22

Assay

98%

form

solid

mp

61-63 °C (lit.)

solubility

H2O: slightly soluble
alcohol: freely soluble
chloroform: freely soluble
diethyl ether: freely soluble

SMILES string

Nc1ccc(I)cc1

InChI

1S/C6H6IN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2

InChI key

VLVCDUSVTXIWGW-UHFFFAOYSA-N

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General description

4-Iodoaniline is the most potent methaemoglobin former.

Application

4-Iodoaniline was used to prepare phenyl functionalized graphene oxide (I-Ph-GO).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ok-Kyung Park et al.
Nano letters, 12(4), 1789-1793 (2012-01-21)
Highly conductive reduced graphene oxide (GO) polymer nanocomposites are synthesized by a well-organized in situ thermochemical synthesis technique. The surface functionalization of GO was carried out with aryl diazonium salt including 4-iodoaniline to form phenyl functionalized GO (I-Ph-GO). The thermochemically
R Mahmud et al.
Toxicology, 117(1), 1-11 (1997-02-14)
The structural basis of dapsone (4,4'-diaminodiphenyl sulphone) haemotoxicity has been determined by investigation of the in vitro bioactivation of a series of 4-substituted arylamines. In the presence of rat liver microsomes, dapsone (100 microM) was the most potent former of
H Yoshida et al.
The Biochemical journal, 248(1), 79-84 (1987-11-15)
Azopigments were obtained from the delta fraction of bilirubin (mammalian biliprotein) in cholestatic sera of men, rats and guinea pigs by diazo reaction with diazotized p-iodoaniline and analysed by t.l.c. Delta bilirubin of men and rats generated both unconjugated and
Iain J McManus et al.
Faraday discussions, 188, 451-466 (2016-04-21)
Porous manganese oxide (OMS-2) and platinum supported on OMS-2 catalysts have been shown to facilitate the hydrogenation of the nitro group in chloronitrobenzene to give chloroaniline with no dehalogenation. Complete conversion was obtained within 2 h at 25 °C and
J C Sinclair et al.
Protein expression and purification, 12(3), 371-380 (1998-05-16)
The N-hydroxyarylamine O-acetyltransferase from Salmonella typhimurium has been expressed as a histidine-tagged fusion protein in Escherichia coli and purified to apparent homogeneity using single-step immobilized metal ion chromatography. Sufficient quantities of the purified protein have been obtained to allow its
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