T0307

Tyloxapol

BioXtra

• Synonym(s): 4-(1,1,3,3-Tetramethylbutyl)phenol polymer with formaldehyde and oxirane
• CAS Number: 25301-02-4
• MDL number: MFCD00149002
• UNSPSC Code: 12161900
• PubChem Substance ID: 24899881
• NACRES: NA.25

Properties

• description: non-ionic
• Quality Level: 100
• product line: BioXtra
• impurities: <0.0005% Phosphorus (P)
• ign. residue: <1.0%
• CMC: 0.018 mM
• transition temp: cloud point 94.3 °C
• anion traces: chloride (Cl^-): <0.05%; sulfate (SO₄^2-): <0.6%
• cation traces: Al: <0.0005%; Ca: <0.0005%; Cu: <0.0005%; Fe: <0.001%; K: <0.005%; Mg: <0.0005%; NH₄⁺: <0.05%; Na: <0.5%; Pb: <0.001%; Zn: <0.0005%
• SMILES string: [H]C([H])=O.OCCO.CC(C)(C)CC(C)(C)c1ccc(O)cc1
• InChI: 1S/C14H22O.C2H6O2.CH2O/c1-13(2,3)10-14(4,5)11-6-8-12(15)9-7-11;3-1-2-4;1-2/h6-9,15H,10H2,1-5H3;3-4H,1-2H2;1H2
• InChI key: GWJOFBXSBDVUMH-UHFFFAOYSA-N

Description

General description

A nonionic liquid polymer of the alkyl aryl polyether alcohol type. Used as a surfactant.

Tyloxapol is a biocompatible surfactant

Application

Tyloxapol has been used in a study to assess the enhanced pulmonary absorption of recombinant human insulin. It has also been used in a study to investigate the metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves