SML1104

NQTrp

≥98% (HPLC)

• Synonym(s): 1,4-Naphthoquinon-2-yl-l-tryptophan, N-(1,4-Dihydro-1,4-dioxo-2-naphthalenyl)-L-tryptophan
• Empirical Formula (Hill Notation): C₂₁H₁₆N₂O₄
• CAS Number: 185351-19-3
• Molecular Weight: 360.36
• MDL number: MFCD21496345
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825479
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: , orange to dark orange-red
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C1C(N[C@H](C(O)=O)CC2=CNC3=C2C=CC=C3)=CC(C4=C1C=CC=C4)=O
• InChI: 1S/C21H16N2O4/c24-19-10-17(20(25)15-7-2-1-6-14(15)19)23-18(21(26)27)9-12-11-22-16-8-4-3-5-13(12)16/h1-8,10-11,18,22-23H,9H2,(H,26,27)/t18-/m0/s1
• InChI key: DZZUYZXINNHEGM-SFHVURJKSA-N

Description

Biochem/physiol Actions

NQTrp is a potent inhibitor of amyloid aggregation (AD). NQTrp completely inhibits Ab oligomerization and fibrillization, and the cytotoxic effect of Ab oligomers in cultured neuronal cell line.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable