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H7157

Sigma-Aldrich

Anti-Hepatocyte Growth Factor antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-HGF

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About This Item

MDL number:
MFCD00212968
UNSPSC Code:
51111800
NACRES:
NA.41

biological source

goat

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 15 μg/mL using human tissue
western blot: 0.1-0.2 μg/mL

UniProt accession no.

P14210

application(s)

research pathology

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HGF(3082)

General description

Hepatocyte Growth Factor (HGF) also refers as Scatter Factor and Hematopoietin A is a 82-85 kD potent mitogen for epithelial cells. It has a critical role in stimulating the growth of hepatocytes, epidermal keratinocytes, Mv1Lu (mink lung epithelial cells), renal tubular epithelial cells, epidermal melanocytes and BALB/MK (mouse keratinocytes) . Anti-Hepatocyte Growth Factor antibody can be used to neutralize the biological activity of recombinant human HGF (rhHGF). Goat anti-Hepatocyte Growth Factor antibody reacts specifically with recombinant human HGF (rhHGF).

Specificity

The antibody will neutralize the biological activity of recombinant human HGF.

Immunogen

recombinant human HGF.

Application

Anti-Hepatocyte Growth Factor antibody can be used in immunohistochemistry and western blotting.

Physical form

Lyophilized from 0.2 μm filtered solution of phosphate buffered saline, pH 7.4, containing 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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R A Furlong
BioEssays : news and reviews in molecular, cellular and developmental biology, 14(9), 613-617 (1992-09-01)
Hepatocyte growth factor, a potent mitogen for epithelial and other cell types, and scatter factor, a stimulant of epithelial cell motility are identical. In addition to these mitogenic and motogenic functions, the factor has been shown to be an epithelial
Jesus Pérez-Hernández et al.
Life (Basel, Switzerland), 11(9) (2021-09-29)
Amoebiasis in humans is caused by the protozoan parasite Entamoeba histolytica, which cytotoxic activity has been demonstrated on a wide variety of target cells. The process involves the adherence of the parasite to the cell, and such adherence is mediated
T Nakamura
Progress in growth factor research, 3(1), 67-85 (1991-01-01)
Hepatocyte growth factor (HGF), a potent mitogen for mature hepatocytes in primary culture, was first found in sera of partial hepatectomized rats and seems to be a hepatotrophic factor for liver regeneration which has not been purified over the past
Rosaria Cammarota et al.
Journal of translational medicine, 8, 112-112 (2010-11-10)
Colorectal cancer can be efficiently treated when found at early stages, thus the search for novel markers is of paramount importance. Since inflammation is associated with cancer progression and angiogenesis, we investigated expression of cytokines like IL-6 and other mediators

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