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34078

Supelco

Oxyclozanide

VETRANAL®, analytical standard

Synonym(s):

2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide, 3,3′,5,5′,6-Pentachloro-2′-hydroxysalicylanilide

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About This Item

Empirical Formula (Hill Notation):
C13H6Cl5NO3
CAS Number:
2277-92-1
Molecular Weight:
401.46
EC Number:
218-904-0
MDL number:
MFCD00864507
UNSPSC Code:
41116107
PubChem Substance ID:
329754798
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Oc1c(Cl)cc(Cl)cc1NC(=O)c2c(O)c(Cl)cc(Cl)c2Cl

InChI

1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)

InChI key

JYWIYHUXVMAGLG-UHFFFAOYSA-N

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General description

Oxyclozanide is an anthelmintic agent, which can show activity against Fasciola hepatica, a parasitic trematode and hence, can be used in the treatment of liver fluke infections.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK0517
BCCJ3689
BCCD2132
BCCC1795
BCBV2215

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Sigma-Aldrich

276855

Dimethyl sulfoxide

Erdal Dinç et al.
Journal of pharmaceutical and biomedical analysis, 28(3-4), 779-788 (2002-05-15)
Four multivariate calibration-prediction techniques, classical least-squares, inverse least-squares, principal component regression and partial least-squares regression were applied to the spectrophotometric multicomponent analysis of a veterinary formulation containing oxfendazole (OXF) and oxyclozanide (OXC) without any separation step. The multivariate calibrations were
B O Fagbemi et al.
Veterinary parasitology, 69(3-4), 231-240 (1997-05-01)
Antigens that were specific to Fasciola gigantica were obtained from the whole worm homogenate of the parasite by immunoaffinity chromatography in cyanogen bromide-activated sepharose 4B columns and used for the production of monoclonal antibodies. The F. gigantica-specific monoclonal antibody was
S A Spence et al.
Australian veterinary journal, 74(6), 456-459 (1996-12-01)
To determine the effect of treating naturally acquired gastrointestinal nematode and paramphistome infections on milk production in dairy cattle. A field trial. One thousand two hundred and thirty nine dairy cows. Cows were either not treated or treated with 4.5
P F Rolfe et al.
Australian veterinary journal, 64(11), 328-332 (1987-11-01)
Controlled tests were used to assess the efficacy of anthelmintics against immature paramphistomes, predominantly Calicophoron calicophorum, in 127 calves which were exposed to contaminated pasture for 7 weeks, treated and slaughtered. When a combination product of oxyclozanide and levamisole was
Treatment of Dicrocoelium dendriticum with a combination of thiophanate and brotianide.
B Tinar et al.
The Veterinary record, 123(25), 650-651 (1988-12-17)
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