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D186201

Sigma-Aldrich

2,3-Dimethylsuccinic acid

≥99%

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About This Item

Linear Formula:
HOOCCH(CH3)CH(CH3)COOH
CAS Number:
Molecular Weight:
146.14
Beilstein:
1723932
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥99%

form

powder

SMILES string

CC(C(C)C(O)=O)C(O)=O

InChI

1S/C6H10O4/c1-3(5(7)8)4(2)6(9)10/h3-4H,1-2H3,(H,7,8)(H,9,10)

InChI key

KLZYRCVPDWTZLH-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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P S Thomas et al.
Postgraduate medical journal, 67(783), 63-65 (1991-01-01)
Chronic lead poisoning has traditionally been treated by parenteral agents. We present a case where a comparison of ethylene diaminetetra-acetic acid was made with 2,3-dimethyl succinic acid (DMSA) which has the advantage of oral administration associated with little toxicity and
G Branlant
European journal of biochemistry, 121(2), 407-411 (1982-01-01)
Aldehyde reductase I from pig liver is strongly inhibited by cyclized NADP--2-oxodiacid adducts. This result, in conjunction with those showing a strong inhibitory effect of certain diacid derivatives, such as (+/-)-dimethylsuccinic acid, towards aldehyde reductase I, suggests the presence of
Birgitta C Burckhardt et al.
Journal of the American Society of Nephrology : JASN, 13(11), 2628-2638 (2002-10-25)
The active transport of Krebs cycle intermediates, such as succinate, alpha-ketoglutarate, and citrate, is mediated by sodium-coupled transporters found in the luminal (NaDC-1) and basolateral plasma membranes (NaDC-3) of proximal tubule cells. This study used the two-electrode voltage clamp technique
E Asante-Appiah et al.
Biochemistry, 36(29), 8710-8715 (1997-07-22)
gem-Dimethylsuccinic acid and its higher homolog, 2-methyl-2-ethylsuccinic acid (MESA) are highly potent inhibitors of both carboxypeptidase A (CPA) and B. The inhibition constant of MESA for CPA (0.11 microM for the racemic mixture) is remarkable considering the relatively simple structure
P H Andersen et al.
Food additives and contaminants, 1(3), 283-288 (1984-07-01)
Three flavourings: dimethyl succinate, ethyl pyruvate and aconitic acid, commonly used in candy, beverages, and baked goods, were tested in the Salmonella/mammalian-microsome test. Tester strains were TA 1535, TA 100, TA 1537 and TA 98 and doses were 32, 160

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