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About This Item
Linear Formula:
CH3OC6H4SO2NH2
CAS Number:
Molecular Weight:
187.22
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Quality Level
Assay
97%
mp
111-115 °C (lit.)
SMILES string
COc1ccc(cc1)S(N)(=O)=O
InChI
1S/C7H9NO3S/c1-11-6-2-4-7(5-3-6)12(8,9)10/h2-5H,1H3,(H2,8,9,10)
InChI key
MSFQEZBRFPAFEX-UHFFFAOYSA-N
General description
4-Methoxybenzenesulfonamide, also known as p-methoxybenzenesulfonamide, is an aromatic sulfonamide. It can undergo polyaddition with vinyloxiranes in the presence of a palladium catalyst.
Application
4-Methoxybenzenesulfonamide may be used in the preparation of S,S-dimethyl-N-p-methoxybenzenesulfonylsulfilimine. It may also be used as a ligand to generate novel bis-tetrahydrofuran–based human immunodeficiency virus (HIV) protease inhibitor.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Palladium (0)-catalyzed polyaddition of bifunctional vinyloxirane with nitrogen nucleophiles. Synthesis of polymers containing an allylamine moiety in the main chain and pendant hydroxyl groups.
Koizumi T, et al.
Macromolecules, 36(15), 5882-5884 (2003)
Carbodiimide-sulfoxide reactions. XII. Reactions of sulfonamides.
The Journal of Organic Chemistry, 36(24), 3686-3691 (1971)
Bis-tetrahydrofuran: a privileged ligand for darunavir and a new generation of hiv protease inhibitors that combat drug resistance.
Arun K Ghosh et al.
ChemMedChem, 1(9), 939-950 (2006-08-24)
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