404861

Tetrakis(hydroxymethyl)phosphonium chloride solution

80% in H₂O

• Synonym(s): THPC solution
• Linear Formula: (HOCH₂)₄PCl
• CAS Number: 124-64-1
• Molecular Weight: 190.56
• Beilstein: 3631669
• MDL number: MFCD00031687
• UNSPSC Code: 12352101
• PubChem Substance ID: 24865276
• NACRES: NA.22

Properties

• form: liquid
• concentration: 80% in H₂O
• refractive index: n20/D 1.512
• density: 1.341 g/mL at 25 °C
• SMILES string: [Cl-].OC[P+](CO)(CO)CO
• InChI: 1S/C4H12O4P.ClH/c5-1-9(2-6,3-7)4-8;/h5-8H,1-4H2;1H/q+1;/p-1
• InChI key: AKXUUJCMWZFYMV-UHFFFAOYSA-M

Description

Application

Tetrakis(hydroxymethyl)phosphonium chloride solution (80% in H₂O) has been used as a reducing agent and stabilizing ligand for the synthesis of gold nanoparticles (AuNPs) from gold(III) chloride trihydrate (HAuCl₄.3H₂O). It is a tetra-functional, amine-reactive, aqueous crosslinker that can be used for tuning the properties of protein-based hydrogels for 3D cell encapsulation applications.

Safety Information

• Pictograms: GHS06,GHS08,GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H290,H301 + H311,H314,H317,H360FD,H410
• Precautionary Statements: P201 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves