1494057

Pancreatin amylase and protease

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: Pancreatin
• Número de CAS: 8049-47-6
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical (small molecule)
• formato: neat

Descripción

Descripción general

Pancreatin amylase and protease USP Reference Standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

• Pancreatin for digestive enzyme research: Pancreatin, a mixture of digestive enzymes including amylase and protease, is extensively used in biochemical studies to understand digestive processes. It is pivotal in research focusing on enzyme mechanisms in the gastrointestinal tract and their role in nutrient absorption and digestion (Saruc et al., 2012).


• High-activity pancreatin for protein digestion studies: The potent activity of pancreatin′s proteolytic and amylolytic enzymes is utilized in scientific studies to dissect the pathways of protein and starch breakdown. This research is fundamental for developing improved therapeutic agents and understanding metabolic diseases linked to protein and carbohydrate metabolism (Gonçalvez et al., 1998).


• Pharmaceutical applications: In the pharmaceutical industry, pancreatin′s enzymes are applied in the formulation of medications that require precise digestive enzymes to activate or enhance drug delivery mechanisms, particularly in treatments targeting the digestive system (Friess et al., 1998).

Definición de unidad

One USP Unit of amylase activity is contained in the amount of pancreatin that decomposes starch at an initial rate such that 0.16 µEq of glycosidic linkage is hydrolyzed per minute under the conditions of the Assay for amylase activity. One USP Unit of protease activity is contained in the amount of pancreatin that under the conditions of the Assay for protease activity hydrolyzes casein at an initial rate such that there is liberated per minute an amount of peptides not precipitated by trichloroacetic acid that gives the same absorbance at 280 nm as 15 nmol of tyrosine.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

This product is part of the USP Biologics program.

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H315,H317,H319,H334,H335
• Consejos de prudencia: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable