1302101

Guanfacine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide
• Fórmula empírica (notación de Hill): C₉H₉Cl₂N₃O · HCl
• Número de CAS: 29110-48-3
• Peso molecular: 282.55
• Número MDL: MFCD00798230
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329749977
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: guanfacine
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical (small molecule)
• formato: neat
• cadena SMILES: Cl.NC(=N)NC(=O)Cc1c(Cl)cccc1Cl
• InChI: 1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H
• Clave InChI: DGFYECXYGUIODH-UHFFFAOYSA-N
• Información sobre el gen: human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

• Reduction of Anxiety-related Reactivity in Primates: Guanfacine hydrochloride mediates anxiety-related reactivity and reduces associated agonistic behavior in two pigtail macaques, showcasing its potential for managing stress and aggression in clinical and veterinary settings (Hopper et al., 2024).


• Enhanced Analgesia for Surgical Procedures: The synergistic interaction of guanfacine with lidocaine enhances cutaneous analgesia, indicating its utility in improving pain management strategies, particularly in surgical environments (Chou et al., 2024).

Acciones bioquímicas o fisiológicas

α-2 noradrenergic receptor agonist.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable