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Merck

1046001

USP

Azathioprine

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine

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About This Item

Fórmula empírica (notación de Hill):
C9H7N7O2S
Número de CAS:
Peso molecular:
277.26
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

azathioprine

fabricante / nombre comercial

USP

aplicaciones

pharmaceutical (small molecule)

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

Cn1cnc(c1Sc2ncnc3[nH]cnc23)[N+]([O-])=O

InChI

1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)

Clave InChI

LMEKQMALGUDUQG-UHFFFAOYSA-N

Información sobre el gen

human ... PPAT(5471)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Azathioprine USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Azathioprine Tablets
  • Azathioprine Sodium for Injection
  • Azathioprine Compounded Oral Suspension

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Pictogramas

Health hazardExclamation mark

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

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Mattheus C B Wielenga et al.
World journal of gastroenterology, 20(44), 16683-16689 (2014-12-04)
To investigate if azathioprine could reduce adenoma formation in Apc(Min/+) , a mouse model of sporadic intestinal tumorigenesis. Azathioprine was administered via drinking water (estimated 6-20 mg/kg body weight per day) to Apc(Min/+) and wildtype mice. Control animals received vehicle
Divya Balakrishnan et al.
Seminars in ophthalmology, 30(2), 157-159 (2013-10-15)
The purpose of this study is to report a case of atypical serpiginous choroiditis presenting with disc edema and exudative retinal detachment, treated successfully with intravenous methyl prednisolone. A 45-year-old male patient presented with sudden decrease of vision in his
Ehren N Rudolph et al.
Transplantation, 99(2), 367-374 (2015-01-17)
Pancreas retransplantation is associated with increased rates of technical failure and rejection compared to other organ transplants. As such, it is not routinely done, and outcomes are mostly known through registry data. Here we analyze the outcomes of primary versus
Rong Fan et al.
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Koji Takeda et al.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 34(1), 89-99 (2014-12-03)
This study assessed the early and late outcomes after cardiac transplantation in patients receiving long-term continuous-flow left ventricular assist device (CF-LVAD) support. Between April 2004 and September 2013, 192 patients underwent HeartMate II (Thoratec, Pleasanton, CA) CF-LVAD placement as a

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