PHL89281

Silychristin

phyproof^® Reference Substance

• Sinónimos: Silymarin II
• Fórmula empírica (notación de Hill): C₂₅H₂₂O₁₀
• Número de CAS: 33889-69-9
• Peso molecular: 482.44
• Número MDL: MFCD00883715
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: primary reference standard
• Línea del producto: phyproof^® Reference Substance
• Análisis: ≥95.0% (HPLC)
• fabricante / nombre comercial: PhytoLab
• aplicaciones: food and beverages
• formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: COc1cc(ccc1O)[C@@H]2Oc3c(O)cc(cc3[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O
• InChI: 1S/C25H22O10/c1-33-18-6-10(2-3-15(18)28)23-14(9-26)13-4-11(5-17(30)25(13)35-23)24-22(32)21(31)20-16(29)7-12(27)8-19(20)34-24/h2-8,14,22-24,26-30,32H,9H2,1H3/t14-,22+,23+,24-/m1/s1
• Clave InChI: BMLIIPOXVWESJG-LMBCONBSSA-N

Descripción

Descripción general

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Aplicación

• Unveiling the healing properties of 2,3-dehydrosilychristin: A silymarin-derived flavonolignan with potent pharmacological activities, highlighting its significance in mitigating oxidative stress and enhancing cellular repair mechanisms in liver tissues (Tripathi et al., 2024).


• Application of SNAP-tag-EGFR cell membrane chromatography model: This study identifies Silychristin as a key antitumor agent in Silybum marianum, detailing its role in targeted cancer therapies and its efficacy in inhibiting tumor cell proliferation (Zhang et al., 2024).


• Pharmaceutical prospects of Silymarin for neurological patients: Provides an update on the neuroprotective properties of Silychristin, emphasizing its therapeutic potential in treating neurological disorders through modulation of oxidative stress and inflammation (Ranjan and Gautam, 2023).


• Structural basis of Nrf2 activation by flavonolignans: Explores how Silychristin, as part of the Silymarin complex, activates the Nrf2 pathway, offering insights into its application in enhancing antioxidant responses at the molecular level (Bello, 2023).


• Mechanistic Insights into the Pharmacological Significance of Silymarin: Reviews the broad pharmacological actions of Silychristin within the Silymarin complex, discussing its anti-inflammatory, antioxidant, and antifibrotic roles, which are pivotal for comprehensive healthcare applications (Wadhwa et al., 2022).

Otras notas

This compound is commonly found in plants of the genus: silybum

Información legal

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P301 + P312 + P330
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable