821834

TOYOPEARL GigaCap^® S-650M Bulk Media

phase sulphonyl, bottle of 250 mL, 75 μm particle size

• Sinónimos: TOYOPEARL GigaCap^® S-650 Cation Exchange Media
• Código UNSPSC: 41115700

Propiedades

• Línea del producto: TOYOPEARL^®
• formulario: slurry
• Características: counter ion Na+
• envase: bottle of 250 mL
• fabricante / nombre comercial: Tosoh 21834
• Parámetros: 3 bar max. pressure
• técnicas: LPLC: suitable
• matriz: hydroxylated methacrylic polymer
• grupo activo de la matriz: sulphonyl phase
• tamaño de partícula: 75 μm
• pH operativo: 3-13
• capacidad: 156 g/L±20 adsorption capacity (hIgG)
• técnica de separación: cation exchange

Descripción

Descripción general

Toyopearl GigaCap S-650 resin is a high capacity, high resolution cation exchange resin* optimized for process scale applications, including the capture and purification of IgG as well as the polishing of monoclonal antibodies. A Toyopearl HW-65 polymeric bead has been chemically modified to provide a higher number of cationic binding sites for increased resin capacity.
While Toyopearl GigaCap S-650M resin was specifically optimized for IgG, with dynamic binding capacities in the vicinity of 140 mg/mL for IgG, it also exhibits high binding capacities for smaller proteins. Typical dynamic binding capacities for lysozyme are in excess of 160 mg/mL.
Toyopearl GigaCap S-650S resin has dynamic binding capacities approaching 165 g/L for gamma globulin. This high capacity, combined with the 35 μm mean particle size, makes Toyopearl GigaCap S-650S ideal for high resolution applications.
Toyopearl GigaCap S-650 resin is stable at high linear velocities, has good pressure-flow characteristics and will withstand back pressures up to 3 bar. The higher capacity and back pressure stability of Toyopearl GigaCap S-650 resin creates opportunities for increased throughput in downstream cation exchange purification steps.
Toyopearl GigaCap S-650M resin also has excellent base stability in 1.0 mol/L NaOH and shows robust clean in place (CIP) properties with minimal loss of capacity after 50 X 1 hour cycles of caustic exposure also using 1.0 mol/L NaOH. (data)
*specifically designed for packed bed use

Especificaciones

Clean in place with 0.5 M NaOH or 0.1 M HCl.

Forma física

72% (v/v) slurry in 20% (v/v) ethanol

Shipped in 20% (v/v) ethanol.

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Información legal

Toyopearl is a registered trademark of Tosoh Corporation

Toyopearl GigaCap is a registered trademark of Tosoh Corporation

Información de seguridad

• Pictogramas: GHS02
• Palabra de señalización: Warning
• Frases de peligro: H226
• Consejos de prudencia: P210 - P233 - P240 - P241 - P242 - P243
• Clasificaciones de peligro: Flam. Liq. 3
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 104.0 °F - closed cup
• Punto de inflamabilidad (°C): 40 °C - closed cup