Z4751

Anti-Zyxin antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Sinónimos: Anti-ESP-2, Anti-HED-2
• Número MDL: MFCD01634364
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: IgG fraction of antiserum
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 82-84 kDa
• reactividad de especies: mouse, human, rat
• técnicas: indirect immunofluorescence: 1:100 using Rat1 cells; western blot (chemiluminescent): 1:1,000 using whole extract of human HeLa cells; western blot (chemiluminescent): 1:2,000 using whole extract of mouse NIH3T3 cells
• Nº de acceso UniProt: Q15942
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... ZYX(7791) ; mouse ... Zyx(22793) ; rat ... Zyx(114636)

Descripción

Descripción general

Zyxin (ZYX ), a zinc-binding phosphoprotein of ∼61kDa is located at focal adhesions and along the actin cytoskeleton. It has three LIM domains. This structural protein is located on human chromosome 7q34.

Inmunógeno

synthetic peptide corresponding to amino acid residues 134-150 of human zyxin with N-terminal added cysteine conjugated to KLH. The corresponding sequence differs by one amino acid in mouse.

Aplicación

Anti-Zyxin antibody has been used in fluorescence microscopy.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 papers)

Acciones bioquímicas o fisiológicas

Zyxin (ZYX ) participates in the modulation of actin assembly at focal adhesions and stress fibers. It also regulates cell adhesion and cell cycle. Overexpression of ZYX is associated with melanoma. Suppression of ZYX  prevents cell growth.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)