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WH0009189M1

Sigma-Aldrich

Monoclonal Anti-ZBED1 antibody produced in mouse

clone 5G1, purified immunoglobulin, buffered aqueous solution

Sinónimos:

Anti-ALTE, Anti-KIAA0785, Anti-TRAMP, Anti-zinc finger, BED-type containing 1

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

5G1, monoclonal

formulario

buffered aqueous solution

reactividad de especies

human

técnicas

indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1-5 μg/mL

isotipo

IgG2aκ

Nº de acceso GenBank

NM_004729

Nº de acceso UniProt

O96006

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... ZBED1(9189)

Descripción general

Zinc finger, BED-type containing 1 (ZBED1), also known as DNA replication-related element-binding factor (DREF), is encoded by the single-exon gene mapped to Xp/Yp PAR region that has a functional homolog on the Y chromosome and escapes X-inactivation.

Inmunógeno

ZBED1 (NP_004720, 3 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
NKSLESSQTDLKLVAHPRAKSKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGNTSNLSYHLEKNHPEEFCEFVKSNTEQMREAFATAFSKLKP

Acciones bioquímicas o fisiológicas

Zinc finger, BED-type containing 1 (ZBED1) function as a crucial transcription factor for cell proliferation, and is implicated in cell cycle-dependent regulation of a number of ribosomal protein (RP) genes. The encoded protein has been suggested to be involved in the transposition of other transposable elements.

Forma física

Solution in phosphate buffered saline, pH 7.4

Información legal

GenBank is a registered trademark of United States Department of Health and Human Services

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sofie Traynor et al.
Nucleic acids research, 47(13), 6668-6684 (2019-05-23)
Rearrangement of the 1q12 pericentromeric heterochromatin and subsequent amplification of the 1q arm is commonly associated with cancer development and progression and may result from epigenetic deregulation. In many premalignant and malignant cells, loss of 1q12 satellite DNA methylation causes
T Esposito et al.
Human molecular genetics, 8(1), 61-67 (1999-01-15)
We report the cloning of a novel gene, called Tramp, in the Xp/Yp PAR region that has a functional homologue on the Y chromosome and escapes X-inactivation. This gene encodes, within a single exon, a putative protein that has amino
Simone Johansen et al.
Genes, 13(1) (2022-01-22)
The transcription factor ZBED1 is highly expressed in trophoblast cells, but its functions in the processes of trophoblast and placental biology remain elusive. Here, we characterized the role of ZBED1 in trophoblast cell differentiation using an in vitro BeWo cell
A Helena Mangs et al.
Current genomics, 8(2), 129-136 (2008-07-29)
The pseudoautosomal regions (PAR1 and PAR2) of the human X and Y chromosomes pair and recombine during meiosis. Thus genes in this region are not inherited in a strictly sex-linked fashion. PAR1 is located at the terminal region of the
Daisuke Yamashita et al.
Molecular and cellular biology, 27(6), 2003-2013 (2007-01-16)
Although ribosomal proteins (RPs) are essential cellular constituents in all living organisms, mechanisms underlying regulation of their gene expression in mammals remain unclear. We have established that 22 out of 79 human RP genes contain sequences similar to the human

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