T4442
Anti-Transforming Growth Factor-β2 antibody produced in goat
affinity isolated antibody, lyophilized powder
Sinónimos:
Anti-TGF-β2
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About This Item
origen biológico
goat
Nivel de calidad
conjugado
unconjugated
forma del anticuerpo
affinity isolated antibody
tipo de anticuerpo
primary antibodies
clon
polyclonal
formulario
lyophilized powder
reactividad de especies
human, pig
técnicas
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
neutralization: suitable
western blot: 0.1-0.2 μg/mL
Nº de acceso UniProt
aplicaciones
research pathology
temp. de almacenamiento
−20°C
modificación del objetivo postraduccional
unmodified
Información sobre el gen
human ... TGFB2(7042)
Descripción general
Transforming Growth Factor-β 2 (TGF-β 2) is a protein produced by many cells and is found in the highest concentration in mammalian bone and porcine platelets. In body fluids like breast milk, amniotic fluid as well as the aqueous and vitreous humor of the eye, the prominent form exist is Latent TGF-β2. It has a pivotal role in regulating invasion in high-grade gliomas by inducing mesenchymal phenotype and remodeling the extracellular matrix. Anti-Transforming Growth Factor-β2 antibody can be used in neutralization and immunohistochemistry. Goat anti-TGF-β 2 antibody reacts specifically with human and porcine TGF-β 2 and TGF-β 1.2. The product has also shown less than 2% cross-reactivity for TGF-β 1, TGF-β 3 and TGF-β 5.
Especificidad
The antibody recognizes TGF-β2 and TGF-β1.2. By immunoblotting (non-reducing conditions) and ELISA, the antibody shows less than 2% cross-reactivity with TGF-β1, TGF-β3, and TGF-β5.
Inmunógeno
porcine transforming growth factor-β2.
Aplicación
Anti-Transforming Growth Factor-β2 antibody can be used in western blotting and ELISA.
Forma física
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Elisabetta Polazzi et al.
Journal of neurochemistry, 110(2), 545-556 (2009-05-22)
Microglia, the immune cells of the CNS, play essential roles in both physiological and pathological brain states. Here we have used an in vitro model to demonstrate neuroprotection of a 48 h-microglial conditioned medium (MCM) towards cerebellar granule neurons (CGNs)
Fusun Baumann et al.
Neuro-oncology, 11(4), 368-380 (2008-11-27)
Lactate dehydrogenase type A (LDH-A) is a key metabolic enzyme catalyzing pyruvate into lactate and is excessively expressed by tumor cells. Transforming growth factor-beta2 (TGF-beta2) is a key regulator of invasion in high-grade gliomas, partially by inducing a mesenchymal phenotype
A B Roberts et al.
Molecular reproduction and development, 32(2), 91-98 (1992-06-01)
The TGF-beta's are multifunctional, pleiotropic molecules with major effects in control of cellular migration, cellular proliferation, and elaboration of extracellular matrix. Thus far, five distinct isoforms of TGF-beta have been described, each approximately 65-85% homologous and containing the characteristic 9
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Chronic non-healing cutaneous wounds are often vulnerable in one or more repair phases that prevent normal healing and pose challenges to the use of conventional wound care modalities. In immunosuppressed subject, the sequential stages of healing get hampered, which may
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