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Merck

T3651

Sigma-Aldrich

Anti-Tropomyosin antibody produced in rabbit

whole antiserum

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

conjugado

unconjugated

forma del anticuerpo

whole antiserum

tipo de anticuerpo

primary antibodies

clon

polyclonal

contiene

15 mM sodium azide

reactividad de especies

chicken

técnicas

indirect immunofluorescence: 1:40 using cultured chicken fibroblasts
western blot: suitable

Nº de acceso UniProt

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

chicken ... TPM1(396366)

Descripción general

Tropomyosin is a rigid, rod shaped protein, closely associated with actin filaments. In non-muscle cells grown in culture, tropomyosin is distributed periodically along the length of the stress fibers.

Especificidad

The antibody specifically reacts with tropomyosin (typical banded pattern of stress fibers) in cultured cells and two tropomyosin bands of total chicken gizzard extract by immunoblotting.

Inmunógeno

smooth muscle tropomyosin from chicken gizzard.

Aplicación

Anti-Tropomyosin antibody produced in rabbit has been used in western immunoblotting and immunofluorescence.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Xu Y, et al.
International Journal of Molecular Medicine, 43(3), 1128-1138 (2019)
Fang Wang et al.
Journal of biomedicine & biotechnology, 2011, 435271-435271 (2011-12-22)
Familial hypertrophic cardiomyopathy (FHC) is a disease of cardiac sarcomeres. To identify molecular mechanisms underlying FHC pathology, functional and structural differences in three FHC-related mutations in recombinant α-Tm (V95A, D175N, and E180G) were characterized using both conventional and modified in
K Miyado et al.
Biochemical and biophysical research communications, 225(2), 427-435 (1996-08-14)
Tropomyosin is an actin-associated cytoskeletal protein expressed in muscle and non-muscle cells. There are several tropomyosin isoforms, and their cellular expression is known to be associated with transformation events caused by retroviral infection and chemical mutagens. We found that expression
Jürg P F Nüesch et al.
Journal of virology, 80(10), 4729-4739 (2006-04-28)
During a productive infection, the prototype strain of the parvovirus minute virus of mice (MVMp) induces dramatic morphological alterations in permissive A9 fibroblasts, culminating in cell lysis at the end of infection. These cytopathic effects (CPE) result from rearrangements and
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Proceedings of the National Academy of Sciences of the United States of America, 104(30), 12482-12487 (2007-07-20)
Autonomous parvoviruses induce severe morphological and physiological alterations in permissive host cells, eventually leading to cell lysis and release of progeny virions. Viral cytopathic effects (CPE) result from specific rearrangements and destruction of cytoskeletal micro- and intermediate filaments. We recently

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