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Merck
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Documentos

SRP6333

Sigma-Aldrich

CD74 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Sinónimos:

DHLAG, HLA class II histocompatibility antigen gamma chain isoform b, HLADG, Ia-GAMMA

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About This Item

Código UNSPSC:
12352200
NACRES:
NA.32

origen biológico

human

recombinante

expressed in E. coli

Análisis

≥90% (SDS-PAGE)

formulario

liquid

mol peso

20.6 kDa (183 aa, 73-232 aa + His tag)

envase

pkg of 100 μg

concentración

0.5 mg/mL

impurezas

<1 EU/μg endotoxin (LAL test)

Nº de acceso UniProt

P04233

Condiciones de envío

dry ice

temp. de almacenamiento

−70°C

Información sobre el gen

human ... CD74(972)

Descripción general

HLA class II histocompatibility antigen gamma chain isoform b, also known as CD74, is a transmembrane protein which, on antigen presenting cells, is the invariant chain that chaperones MHC class II dimers from the endoplasmic reticulum to the cell surface. CD74 is expressed by cells of both T lymphocyte and B lymphocyte lineages. It is upregulated in several cancers and is also expressed by nonimmune cells during inflammation. Recombinant human CD74 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Forma física

0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 1 mM DTT and 30% glycerol.

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H319

Clasificaciones de peligro

Eye Irrit. 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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