SML3464

Gossypetin

≥98% (HPLC), MKK3 and MKK6 protein kinases inhibitor, powder

• Sinónimos: 2-(3,4-Dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-1-benzopyran-4-one, 8-Hydroxyquercetin, Articulatidin, Equisporol
• Fórmula empírica (notación de Hill): C₁₅H₁₀O₈
• Número CAS: 489-35-0
• Peso molecular: 318.24
• NACRES: NA.77
• UNSPSC Code: 12352200
• MDL number: MFCD00017680
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Nombre del producto: Gossypetin, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: , light green to yellow
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: OC1=CC(O)=C2C(C(O)=C(OC2=C1O)C3=CC=C(C(O)=C3)O)=O
• InChI: 1S/C15H10O8/c16-6-2-1-5(3-7(6)17)14-13(22)12(21)10-8(18)4-9(19)11(20)15(10)23-14/h1-4,16-20,22H
• InChI key: YRRAGUMVDQQZIY-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Antioxidant, antibacterial, anticancer; potent inhibitor of MKK3 and MKK6 protein kinases

Gossypetin is a hexahydroxylated flavonoid found in the flowers and the calyx of Hibiscus, which exhibits numerous pharmacological effects, including antioxidant, antibacterial and anticancer activities. It induces apoptosis and autophagic cell death in prostate cancer cells. Gossypetin is a potent inhibitor of MKK3 and MKK6 protein kinases that suppresses esophageal cancer growth.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable