SML2474

HS56

≥98% (HPLC)

• Sinónimos: 2-[[1-(3-Chlorophenyl)-4,5-dihydro-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-6-yl]thio]acetonitrile
• Fórmula empírica (notación de Hill): C₁₃H₈ClN₅OS
• Número CAS: 922050-57-5
• Peso molecular: 317.75
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C1NC(SCC#N)=NC2=C1C=NN2C3=CC(Cl)=CC=C3

Descripción

Biochem/physiol Actions

HS56 is a highly selective and potent dual Pim/DAPK3 inhibitor that significantly reduces contractile intensity and phosphorylation levels of myosin light chain (LC20) in rat caudal arterial smooth muscle strips. HS56 decreases blood pressure in spontaneously hypertensive mice without affecting heart rate.

highly selective and potent dual Pim/DAPK3 inhibitor that significantly reduces contractile intensity and phosphorylation levels of myosin light chain (LC20)

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable