SML0997

ML 230

≥98% (HPLC)

• Sinónimos: (4-(5-(Furan-2-yl)-2-phenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl)(furan-3-yl)methanone, CID44640177, KSC-6-131-1, SID 88095709
• Fórmula empírica (notación de Hill): C₂₅H₂₁N₅O₃
• Peso molecular: 439.47
• Código UNSPSC: 12161501
• NACRES: NA.77

Propiedades

• Ensayo: ≥98% (HPLC)
• Formulario: powder
• color: white to beige
• solubilidad: DMSO: 10 mg/mL, clear
• temp. de almacenamiento: 2-8°C

Descripción

Acciones bioquímicas o fisiológicas

ML 230 (SID 88095709) is a specific inhibitor of the ABC-binding cassette trasporter BCRP (MRP-1; ABCG2).

ML 230 (SID 88095709) is a specific inhibitor of the ABC-binding cassette trasporter BCRP (MRP-1; ABCG2). The compound ML 230 is 36-fold selective for BCRP over MDR-1 (Pgp; ABCB1) with IC₅₀ values of 0.013 and 4.7 mM, respectively.

Características y beneficios

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Información de seguridad

• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable