SAB5801051

Alpaca Anti-Chicken IgY HRP single domain Antibody

recombinant Alpaca(VHH) Nano antibody

• Sinónimos: Recombinant Alpaca single variable domain secondary Nanobody
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: alpaca
• recombinante: expressed in E. coli
• conjugado: horse radish peroxidase (HRP)
• forma del anticuerpo: affinity purified immunoglobulin
• tipo de anticuerpo: secondary antibodies
• clon: recombinant monoclonal
• formulario: lyophilized solid
• mol peso: 14 kDa
• reactividad de especies: chicken, Alpaca
• técnicas: ELISA: 1:10000-1:50000; western blot: 1:10000-1:50000
• tamaño: 0.1 mL
• color: colorless
• isotipo: VHH
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C

Descripción

Descripción general

Alpaca Anti-Chicken IgY HRP single domain Antibody is designed to specifically detect chicken IgY. It is a monovalent, single domain, recombinant antibody to chicken IgY coupled to HRP. Based on immunoelectrophoresis and/or ELISA, Alpaca Anti-Chicken IgY HRP single domain Antibody detects the chicken IgY selectively but not with mouse, rabbit, human, cynomolgus, rat, goat IgG.

Hens egg yolk immunoglobulins IgY can be transferred from the serum of mother hen to the offspring egg yolk to acquire immunity. In the immunodiagnostic technologies, IgY is an excellent antibody for using in immunological assays involving mammalian sera, due to discriminative properties of IgY compared to mammalian IgG, as IgY does not react with the rheumatoid factor and human anti-mouse IgG antibodies do not activate the complement system and do not bind to Fc receptor. Also, they have poor cross reactivity to mammalian IgG due to immunological differences. IgY does not contain a hinge region but does contain an additional constant domain. The whole IgY molecule possesses both the Fc region and the Fab region, which possessing the epitope-recognition site. The IgYcontains two heavy and light chains. The common IgY is monomeric with a molecular weight of approximately 170 kDa.

VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(less than15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.

Especificidad

Fc region of chicken IgY
Isotype: VHH domain of alpaca IgG2b/2c

Inmunógeno

Recombinant Alpaca single variable domain secondary nano antibody

Envase

100 μg in Glass bottle

Forma física

Lyophilized from 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose

Reconstitución

Add 100uL dH2O or 100uL dH2O with 50% Glycerol to a final concentration of 1mg/mL

Almacenamiento y estabilidad

After reconstitution, store at –20 °C(Avoid freeze / thaw cycles). Protect from light. Stable for 12 months at -20°C

Otras notas

No cross-reactivity with mouse, rabbit, human, cynomolgus, rat, goat IgG

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H317,H412
• Consejos de prudencia: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Clasificaciones de peligro: Aquatic Chronic 3 - Skin Sens. 1
• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable