SAB5702738

Anti-LIN28A Antibody, clone 2S1I10, Rabbit Monoclonal

• Sinónimos: CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A
• Código UNSPSC: 12352203
• NACRES: NA.46

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• Materiales: colorless
• clon: 2S1I10, monoclonal
• formulario: liquid
• mol peso: 26 kDa
• reactividad de especies: human, rat, rat
• concentración: 0.70 mg/mL
• técnicas: immunofluorescence: 1:50 - 1:200; western blot: 1:10000 - 1:20000
• color: colorless
• isotipo: IgG
• secuencia del inmunógeno: MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKS
• Nº de acceso UniProt: Q9H9Z2
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... LIN28A(79727)

Descripción

Descripción general

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]

Inmunógeno

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LIN28A (Q9H9Z2).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Aplicación

WB, IF/ICC

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1