SAB5702154

Anti-Neurofilament H (200 kDa) Antibody

rabbit monoclonal, 7L2V7

• Sinónimos: CMT2CC,NFH,NEFH
• Código UNSPSC: 12352203
• NACRES: NA.46

Propiedades

• product name: Anti-Neurofilament H Antibody, clone 7L2V7, Rabbit Monoclonal,
• origen biológico: rabbit
• Nivel de calidad: 100
• Materiales: colorless
• clon: 7L2V7, monoclonal
• formulario: liquid
• reactividad de especies: rat, human, rat
• concentración: 1.41 mg/mL
• técnicas: immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• color: colorless
• isotipo: IgG
• secuencia del inmunógeno: AKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE
• Nº de acceso UniProt: P12036
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... NEFH(4744)

Descripción

Descripción general

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]

Inmunógeno

A synthetic peptide corresponding to a sequence within amino acids 550-650 of human Neurofilament H (P12036).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Aplicación

WB, IHC, IF/ICC, IP

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1