SAB5701695

Anti-LIN28B antibody produced in rabbit

• Código UNSPSC: 12352203
• NACRES: NA.43

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• tipo de anticuerpo: primary antibodies
• clon: monoclonal
• formulario: liquid
• reactividad de especies: mouse, rat, human
• concentración: 0.53 mg/mL
• técnicas: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• Nº de acceso UniProt: Q6ZN17
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... LIN28B(389421)

Descripción

Descripción general

The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]

Inmunógeno

A synthesized peptide derived from human LIN28B

Forma física

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable