SAB5700030

Anti-RHOC antibody produced in rabbit

• Sinónimos: ARH9, ARHC, H9, RHOC, RHOH9
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: 22
• reactividad de especies: human, rat, mouse
• concentración: 1.99 mg/ml
• técnicas: immunofluorescence: 1:50-1:100; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:2000
• Nº de acceso UniProt: P08134
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... RHOC(389)

Descripción

Descripción general

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Inmunógeno

Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human RHOC (NP_001036144.1).

Forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Almacenamiento y estabilidad

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable