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SAB5200110

Sigma-Aldrich

Anti-AQP2 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

Sinónimos:

Anti-AQP-CD, Anti-AQP2, Anti-AQPCD, Anti-Aquaporin 2

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous glycerol solution

mol peso

antigen predicted mol wt 28.8 kDa

reactividad de especies

human, mouse, rat

concentración

1 mg/mL

técnicas

indirect immunofluorescence: suitable
western blot: suitable

Nº de acceso NCBI

NP_037041.2

Nº de acceso UniProt

P41181

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

rat ... Aqp2(25386)

Categorías relacionadas

Descripción general

The gene ID of the protein aquaporin-2 (AQP2) is 25386.

Especificidad

Detects ~28.8 kDa. May detect larger glycosylated bands ~35-50 kDa.

Inmunógeno

C-terminal peptide

Acciones bioquímicas o fisiológicas

Aquaporin 2 (AQP2) takes part in maintaining the water balance in cells. A high concentration of the protein has been observed in rats during hypothyroidism.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

PBS, pH 7..4, 50% glycerol, and 0.09% sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Peter Kösters et al.
Cells, 13(10) (2024-05-24)
Uncovering the function of understudied G protein-coupled receptors (GPCRs) provides a wealth of untapped therapeutic potential. The poorly understood adhesion GPCR Gpr126 (Adgrg6) is widely expressed in developing kidneys. In adulthood, Gpr126 expression is enriched in parietal epithelial cells (PECs)
Lorena I Sarati et al.
Metabolism: clinical and experimental, 62(9), 1287-1295 (2013-05-28)
Hypothyroid state and aging are associated with impairment in water reabsorption and changes in aquaporin water channel type 2 (AQP2). Nitric oxide (NO) is involved in AQP2 trafficking to the apical plasma membrane in medullary collecting duct cells. The purpose
Salvador Cazorla-Vázquez et al.
Cells, 12(15) (2023-08-11)
Adhesion G protein-coupled receptors (aGPCRs) comprise the second-largest class of GPCRs, the most common target for approved pharmacological therapies. aGPCRs play an important role in development and disease and have recently been associated with the kidney. Several aGPCRs are expressed
William J Monis et al.
The Journal of cell biology, 216(7), 2131-2150 (2017-06-04)
Primary cilia perceive the extracellular environment through receptors localized in the ciliary membrane, but mechanisms directing specific proteins to this domain are poorly understood. To address this question, we knocked down proteins potentially important for ciliary membrane targeting and determined
Naohiro Nomura et al.
American journal of physiology. Cell physiology, 307(7), C597-C605 (2014-06-20)
A reduction or loss of plasma membrane aquaporin 2 (AQP2) in kidney principal cells due to defective vasopressin (VP) signaling through the VP receptor causes excessive urine production, i.e., diabetes insipidus. The amount of AQP2 on the plasma membrane is

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