SAB4702004

Monoclonal Anti-NG2 PE produced in mouse

• Sinónimos: CSPG4, Chondroitin sulfate proteoglycan 4, MCSP, MSK16
• Código UNSPSC: 12352203

Propiedades

• conjugado: phycoerythrin (R-PE) conjugate
• Nivel de calidad: 100
• tipo de anticuerpo: primary antibodies
• clon: 7.1, monoclonal
• formulario: buffered aqueous solution
• reactividad de especies: human
• técnicas: flow cytometry: suitable
• isotipo: IgG1
• Nº de acceso UniProt: Q6UVK1
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CSPG4(1464)

Descripción

Descripción general

NG2 / chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.

Especificidad

The mouse monoclonal antibody 7.1 recognizes an extracellular epitope of NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.

Inmunógeno

Human bone marrow stromal cells infected with SV-40

Forma física

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Nota de preparación

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Almacenamiento y estabilidad

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Otras notas

The antibody solution should be gently mixed before use.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable