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SAB4503912

Sigma-Aldrich

Anti-phospho-ETS1 (pThr38) antibody produced in rabbit

affinity isolated antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

mol peso

antigen 50 kDa

reactividad de especies

rat, human, mouse

concentración

~1 mg/mL

técnicas

ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

Nº de acceso NCBI

P14921

Nº de acceso UniProt

P14921

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

phosphorylation (pThr38)

Información sobre el gen

human ... ETS1(2113)

Descripción general

ETS1 (E26 transformation specific sequence 1) is a proto‐oncogene. It is a member of the family of ETS transcriptional factors. ETS1 is usually expressed in lymphoid cells. This gene is mapped to human chromosome 11q24.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human ETS1 around the phosphorylation site of Thr38.

Immunogen Range: 11-60

Acciones bioquímicas o fisiológicas

ETS1 (E26 transformation specific sequence 1) participates in Pol ι‐mediated progression of ESCC (esophageal squamous cell carcinoma). This gene controls cancer cell invasion, metastasis and EMT (epithelial to mesenchymal transition). ETS1 also plays important roles in the lymphocyte development, function, apoptosis and inflammation.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Submicroscopic deletions of 11q24-25 in individuals without Jacobsen syndrome: re-examination of the critical region by high-resolution array-CGH
Tyson C, et al.
Molecular Cytogenetics (2008)
Phosphorylation of ETS-1 is a critical event in DNA polymerase iota-induced invasion and metastasis of esophageal squamous cell carcinoma
He C, et al.
Cancer Science, 108(12), 2503-2510 (2017)
Association of E26 Transformation Specific Sequence 1 Variants with Rheumatoid Arthritis in Chinese Han Population
Chen L, et al.
PLoS ONE, 10(8) (2015)
Yingxue Hao et al.
MedComm, 4(1), e202-e202 (2023-01-14)
The regenerative capacity of skeletal muscle is dependent on satellite cells. The circadian clock regulates the maintenance and function of satellite cells. Cryptochrome 2 (CRY2) is a critical component of the circadian clock, and its role in skeletal muscle regeneration

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