SAB4503712

Anti-GAB2 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: GRB2-associated binder 2, GRB2-associated-binding protein 2, Growth factor receptor bound protein 2-associated protein 2, KIAA0571, pp100
• Número MDL: MFCD02686157
• Código UNSPSC: 12352203

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 74 kDa
• reactividad de especies: rat, human, mouse
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Nº de acceso NCBI: Q9UQC2
• Nº de acceso UniProt: Q9UQC2
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... GAB2(9846)

Descripción

Descripción general

Anti-GAB2 Antibody detects endogenous levels of total GAB2 protein.

GAB2 (GRB2 associated binding protein 2), a mammalian homolog of GAB1 is a member of the family of insulin receptor substrate 1-like multi-substrate proteins. It is located on human chromosome 11q14.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human Gab2.

Immunogen Range: 125-174

Acciones bioquímicas o fisiológicas

GAB2 (GRB2 associated binding protein 2) plays a major role in proliferation, survival and differentiation. It induces the multiplication of cells by initiating the extracellular signal-regulated kinase (ERK) signaling pathway in hepatocellular carcinoma.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable