SAB4500869

Anti-CD32 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: CD32, CDW32, FC γ receptor IIB, FC-γ RII, FC-γ RII-B
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 34 kDa
• reactividad de especies: human, rat, mouse
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:1000; western blot: 1:500-1:1000
• Nº de acceso NCBI: P31994
• Nº de acceso UniProt: P31994
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... FCGR2B(2213)

Descripción

Descripción general

The human immune system has six FcγRs-FcγRI, FcγRIIA, FcγRIIB, FcγRIIC, FcγRIIIA and FcγRIIIB. FcγRIIIB/CD32 (Fc fragment of IgG receptor IIb) is an inhibitory receptor that is located on human chromosome 1q23.

Anti-CD32 Antibody detects endogenous levels of total CD32 protein.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human CD32.

Immunogen Range: 277-326

Acciones bioquímicas o fisiológicas

FcγRIIIB/CD32 (Fc fragment of IgG receptor IIb) controls the generation of autoantibodies and their effector roles. During a viral memory response, FcγRIIB blocks the generation of inflammatory type I IFN from plasmacytoid dendritic cells.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable