SAB4500397

Anti-Collagen XIII α1 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: CODA1, COLXIIIA1, Collagen α-1(XIII) chain
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 69 kDa
• reactividad de especies: human, mouse
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:20000; immunofluorescence: 1:100-1:500
• Nº de acceso NCBI: Q5TAT6
• Nº de acceso UniProt: Q5TAT6
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... COL13A1(1305)

Descripción

Descripción general

The COL13A1 (collagen type XIII α-1 chain) gene is mapped to human chromosome 10q22.1. It codes for the α-chain of a group of non-fibrillar collagen. The protein is homotrimeric containing a single transmembrane region with intracellular and extracellular domains. The ectodomain contains three alternating collagenous and non-collagenous domains. COL13A1 is expressed in the muscle motor endplate. Anti-Collagen XIII α1 Antibody detects endogenous levels of total Collagen XIII α1 protein.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human Collagen XIII alpha1.

Immunogen Range: 641-690

Acciones bioquímicas o fisiológicas

Collagen XIII α1 (COL13A1) is an oncogene, promoting invasion in cancer. Upregulation of COL13A1 gene is observed in bladder cancer. COL13A1 is associated with neuromuscular junction organization. Mutation in the gene leads to myasthenic disorder.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable