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SAB4301578

Sigma-Aldrich

Anti-phospho-ERK1/2 (pThr202/Tyr204) antibody produced in rabbit

affinity isolated antibody

Sinónimos:

ERK-1, ERK1, ERT2, P44ERK1, PRKM3

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

mol peso

42 kDa
 44 kDa

reactividad de especies

rat, mouse, human

concentración

1.0 mg/mL

técnicas

western blot: 1:500-1:1000 (Cell Lysate)

isotipo

IgG

nº de acceso

NP_001035145.1 

Nº de acceso UniProt

P27361

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

phosphorylation (pThr202/pTyr204)

Información sobre el gen

human ... MAPK3(5595)

Especificidad

The antibody detects endogenous level of p44/42 MAP Kinase only when phosphorylated at Threonine 202 and Tyrosine 204 .

Inmunógeno

Peptide sequence around phosphorylation site of Threonine 202/Tyrosine 204(F-L-T(p)-E-Y(p)-V-A) derived from Human p44/42 MAP Kinase.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Varun Kumar et al.
Current eye research, 46(5), 710-718 (2020-10-28)
Understanding molecular changes is essential for designing effective treatments for nonarteritic anterior ischemic optic neuropathy (AION), the most common acute optic neuropathy in adults older than 50 years. We investigated changes in the mitogen-activated protein kinase (MAPK) pathway after experimental AION
Lenka Halova et al.
Open biology, 11(4), 200405-200405 (2021-04-08)
Fluctuations in TOR, AMPK and MAP-kinase signalling maintain cellular homeostasis and coordinate growth and division with environmental context. We have applied quantitative, SILAC mass spectrometry to map TOR and nutrient-controlled signalling in the fission yeast Schizosaccharomyces pombe. Phosphorylation levels at
Vittorio Perfetti et al.
Oncotarget, 8(34), 56158-56167 (2017-09-17)
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs express the receptor tyrosine kinase KIT, and the majority of GISTs present KIT gain-of-function mutations that cluster in the 5' end of the receptor juxtamembrane
Ravinder K Goyal et al.
BMC genomics, 19(1), 178-178 (2018-03-07)
The mitogen-activated protein kinase (MAPK) family is involved in signal transduction networks that underpin many different biological processes in plants, ranging from development to biotic and abiotic stress responses. To date this class of enzymes has received little attention in
Guangchao Zhao et al.
Rejuvenation research, 22(4), 325-334 (2018-11-10)
It is known that preconditional treatment with volatile anesthetics can induce tolerance of the brain to stroke. A previous study demonstrated that the involvement of TREK-1, a two-pore domain K+ channel, in sevoflurane preconditioning induced neuroprotection against focal cerebral ischemia
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