SAB4301041

Anti-CD163 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: M130, MM130
• Código UNSPSC: 12352203

Propiedades

• origen biológico: rabbit
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• reactividad de especies: human
• concentración: 2.9 mg/mL
• técnicas: immunohistochemistry: 1:25- 1:100
• isotipo: IgG
• nº de acceso: NP_004235.4
• Nº de acceso UniProt: Q86VB7
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CD163(9332)

Descripción

Descripción general

Cluster of differentiation 163 (CD163) is a hemoglobin scavenger receptor, encoded by a gene mapped to human chromosome 12p13.31. It is expressed on the surface of activated macrophages. The encoded protein is a member of scavenger receptor cysteine-rich family (SRCR) and is specifically expressed on cells of the monocyte/macrophage lineage.

Especificidad

The antibody detects endogenous levels of total CD163 protein.

Inmunógeno

Synthetic peptide corresponding to residues near the C terminal of human CD163 molecule

Acciones bioquímicas o fisiológicas

Cluster of differentiation 163 (CD163) modulates anti-inflammatory functions and has a role in hemoglobin-haptoglobin clearance. Various cytokines influence the expression of CD163. It may be associated with hepatocellular carcinoma. Soluble CD163 level in serum acts as a potent indicator of the progression of cirrhosis and portal hypertension.

Características y beneficios

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Forma física

Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable