SAB4300617

Anti-phospho-Cdc25b (pSer¹⁴⁹) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-AI604853 antibody produced in rabbit, Anti-Cdc25b antibody produced in rabbit, Anti-cell division cycle 25 homolog B (S. pombe) antibody produced in rabbit
• Número MDL: MFCD01633249
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: ~62 kDa
• reactividad de especies: mouse
• concentración: 1 mg/mL
• técnicas: western blot: 1:500-1:1000
• isotipo: IgG
• secuencia del inmunógeno: (F-R-SP-L-P)
• Nº de acceso NCBI: NP_001104545.1
• Nº de acceso UniProt: P30306
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer149)
• Información sobre el gen: mouse ... Cdc25b(12531)

Descripción

Inmunógeno

Peptide sequence around phosphorylation site of Serine 149 (F-R-S(p)-L-P).according to the protein Cdc25b.

Características y beneficios

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Descripción de destino

Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.

Forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable