SAB4300071

Anti-phospho-CAV1 (pTyr¹⁴) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-BSCL3 antibody produced in rabbit, Anti-CAV antibody produced in rabbit, Anti-CGL3 antibody produced in rabbit, Anti-MSTP085 antibody produced in rabbit, Anti-caveolin 1, caveolae protein, 22kDa antibody produced in rabbit
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: ~24 kDa
• reactividad de especies: mouse, rat, human
• concentración: 1 mg/mL
• técnicas: indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotipo: IgG
• secuencia del inmunógeno: (H-L-YP-T-V)
• Nº de acceso NCBI: NP_001166366.1
• Nº de acceso UniProt: Q03135
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pTyr14)
• Información sobre el gen: human ... CAV1(857)

Descripción

Inmunógeno

Peptide sequence around phosphorylation site of tyrosine 14 (H-L-Y(p)-T-V), according to the protein CAV1.

Características y beneficios

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Descripción de destino

The scaffolding protein encoded by Caveolin-1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.

Forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable