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Merck
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SAB1305567

Sigma-Aldrich

Anti-β-Actin (ACTB) Antibody

mouse monoclonal, 8H10D10

Sinónimos:

ACTB, Actin, cytoplasmic 1, Actin, cytoplasmic 1, N-terminally processed, Beta-actin

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

Nombre del producto

MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse, clone 8H10D10, crude ascites, buffered aqueous solution

origen biológico

mouse

forma del anticuerpo

crude ascites

tipo de anticuerpo

primary antibodies

clon

8H10D10, monoclonal

Formulario

buffered aqueous solution

mol peso

41737 Da

reactividad de especies

human

técnicas

immunohistochemistry: 1:10-1:50
western blot: 1:5000-1:20000

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... ACTB(60)

Descripción general

ACTB (actin β) gene codes for β-actin. It is a cytoskeletal housekeeping protein. It is present in the cytoplasm. This gene is located on human chromosome 7p22.1.

Aplicación

MONOCLONAL ANTI-BETA-ACTIN antibody has been used in western blotting.

Acciones bioquímicas o fisiológicas

β-Actin modulates cell growth, migration and the G-actin pool. Mutations in ACTB leads to pleiotropic developmental disorder.

Forma física

Supplied in PBS with 0.09% (W/V) sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Opcional

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

12 - Non Combustible Liquids

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Lisa Mutschelknaus et al.
Scientific reports, 7(1), 12423-12423 (2017-10-01)
Radiation is a highly efficient therapy in squamous head and neck carcinoma (HNSCC) treatment. However, local recurrence and metastasis are common complications. Recent evidence shows that cancer-cell-derived exosomes modify tumour cell movement and metastasis. In this study, we link radiation-induced
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Mutschelknaus L, et al.
Scientific Reports, 7(1), 12423-12423 (2017)
Gabriela M Wright et al.
PloS one, 16(6), e0252927-e0252927 (2021-06-18)
Theoretically, small molecule CDK4/6 inhibitors (CDK4/6is) represent a logical therapeutic option in non-small cell lung cancers since most of these malignancies have wildtype RB, the key target of CDKs and master regulator of the cell cycle. Unfortunately, CDK4/6is are found
Xinjun Lin et al.
Experimental and therapeutic medicine, 16(1), 204-212 (2018-06-14)
The present study aimed to evaluate the impact of dendrobium mixture (DMix) on the gene and protein expression of insulin signaling pathway-associated factors in the livers of diabetic rats. The molecular mechanisms by which DMix inhibits gluconeogenesis were also investigated.
Lisa Mutschelknaus et al.
PloS one, 11(3), e0152213-e0152213 (2016-03-24)
Exosomes are nanometer-sized extracellular vesicles that are believed to function as intercellular communicators. Here, we report that exosomes are able to modify the radiation response of the head and neck cancer cell lines BHY and FaDu. Exosomes were isolated from

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