SAB1300556

Anti-NR6A1 (C-term) antibody produced in rabbit

Ig fraction of antiserum, buffered aqueous solution

• Sinónimos: Anti-GCNF, Anti-Germ cell nuclear factor, Anti-HGCNF, Anti-RTR, Retinoid receptor-related testis-specific receptor
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: Ig fraction of antiserum
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• reactividad de especies: human
• técnicas: indirect ELISA: 1:1000; western blot: 1:100-1:500
• Nº de acceso NCBI: NP_201591
• Nº de acceso UniProt: Q15406
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... NR6A1(2649)

Descripción

Descripción general

NR6A1 has been shown to affect gene expression in embryogenesis and spermatogenesis and is essential for embryonic survival and normal development. Loss of NR6A1 causes embryonic lethality and disrupts normal somitogenesis as well as neural-tube and axis formation. NR6A1 binds as a homodimer to the DR0 DNA response element and has been shown to regulate transcription of genes including protamines 1 and 2 and Oct4. NR6A1 repression function has been shown to be mediated by interaction with the co-repressors N-COR and SMRT in the absence of ligand.

Inmunógeno

NR6A1 (NP_201591, 340-375)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human NR6A1.

Forma física

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable