SAB1104559

Anti-NUPR1 (47-60) antibody produced in rabbit

IgG fraction of antiserum

• Sinónimos: Anti-COM1, Anti-Nuclear protein, transcriptional regulator, 1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: IgG fraction of antiserum
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen predicted mol wt ~9 kDa
• reactividad de especies: human
• técnicas: western blot: 1:500-1:2,000
• Nº de acceso UniProt: O60356
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... NUPR1(26471)

Descripción

Descripción general

The NUPR1 (nuclear protein 1, transcriptional regulator) gene is mapped to human chromosome 16p11.2 and encodes a chromatin remodeling protein of 8.8 KDa.

Inmunógeno

synthetic peptide corresponding to amino acids 47-60 of human NUPR1

Aplicación

Anti-NUPR1 (47-60) antibody produced in rabbit has been used in western blot analysis.

Acciones bioquímicas o fisiológicas

Nupr1 (nuclear protein 1, transcriptional regulator) is a stress response factor, induced by lipopolysaccharides, CCl₄, starvation, cell cycle arrest and other protein stimuli. NUPR1 is associated with tumor cell proliferation, metastasis and apoptosis, also regulates entosis, matrix remodeling and autophagy. It serves as a substrate for protein kinase A. Overexpression of this gene is observed in glioblastoma and hepatocellular carcinoma. The protein function is tissue specific and differs at molecular level. It can act as a tumor suppressor or inducer.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable