S5013

Salbutamol hemisulfate salt

≥98%

• Sinónimos: α-([t-Butylamino]methyl)-4-hydroxy-m-xylene-α,α′-diol, Albuterol
• Fórmula lineal: C₁₃H₂₁NO₃ · 1/2H₂SO₄
• Número de CAS: 51022-70-9
• Peso molecular: 288.35
• Número CE: 256-916-8
• Número MDL: MFCD00055200
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24277746
• NACRES: NA.77

Propiedades

• Análisis: ≥98%
• solubilidad: 1 M NaOH: 50 mg/ml, clear to slightly hazy, yellow-green
• emisor: GlaxoSmithKline
• cadena SMILES: OS(O)(=O)=O.CC(C)(C)NCC(O)c1ccc(O)c(CO)c1.CC(C)(C)NCC(O)c2ccc(O)c(CO)c2
• InChI: 1S/2C13H21NO3.H2O4S/c2*1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h2*4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4)
• Clave InChI: BNPSSFBOAGDEEL-UHFFFAOYSA-N
• Información sobre el gen: human ... ADRB2(154)

Descripción

Aplicación

Salbutamol hemisulfate salt has been used as reference standards of drugs for the validation of β-agonist residue.

Salbutamol hemisulfate salt was used as standard in analysis of fortified meat for LABA content using ELISA kits.³ It was used to study the response of prostaglandin 2α to various β-adrenergic agonists in cultured bovine endometrial cells.⁴

Acciones bioquímicas o fisiológicas

Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP). Salbutamol is particularly effective in treatment of asthma as it provides immediate relief. Salbutamol is one of the most popular short-acting BA (SABA). It is useful in treating the symptoms of EIB (exercise induced bronchospasm).

Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP).¹ Salbutamol is particularly effective in treatment of asthma as it provides immediate relief.²

β2-Adrenergic receptor agonist.

Características y beneficios

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de señalización: Warning
• Frases de peligro: H317,H351,H361fd
• Consejos de prudencia: P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
• Clasificaciones de peligro: Carc. 2 - Repr. 2 - Skin Sens. 1
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)