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S0756

Sphingomyelin

from chicken egg yolk, ≥95%

Sinónimos:

N-Acyl-4-sphingenyl-1-O-phosphorylcholine, N-Acyl-D-sphingosine-1-phosphocholine

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A ustedes/SKUDisponibilidadPrecio
50 mg
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154,00 €
100 mg
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239,00 €
500 mg
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825,00 €

Acerca de este artículo

Número CAS:
UNSPSC Code:
12352211
NACRES:
NA.25
EC Number:
286-097-2
MDL number:

154,00 €


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biological source

chicken egg yolk

Quality Segment

assay

≥95%

form

powder

solubility

chloroform/methanol: soluble 50 mg/mL, clear, colorless to faintly yellow (1:1)

functional group

phospholipid

lipid type

sphingolipids

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCC/C=C/[C@H]([C@@H](NC=O)COP(O)(OCC[N+](C)(C)C)=O)O

InChI

1S/C24H49N2O6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(28)23(25-22-27)21-32-33(29,30)31-20-19-26(2,3)4/h17-18,22-24,28H,5-16,19-21H2,1-4H3,(H-,25,27,29,30)/p+1/b18-17+/t23-,24+/m0/s1

InChI key

LRYZPFWEZHSTHD-HEFFAWAOSA-O

General description

Sphingomyelin (SM) is a principal sphingolipid in mammalian cell membranes. Its biological functions have been studied.

Application

Sphingomyelin is suitable for use:
  • in the preparation of standard during the enzymatic measurement of plasma sphingomyelin levels[1]
  • to study the binding of Vascular Anticoagulant α (VAC α) to planar phospholipid bilayers[2]
  • to perform fluorescence polarization of PC16 (N-[α-N-palmitoyl-ε-N-(4-nitrobenz-2-oxa-1,3-diazole)-L-lysine]-2-aminoethanol-N- (trimethylaminoethanol) phosphate) in dispersions of co-sonicated lecithin and sphingomyelin[3]
  • for reconstitution of viral ion channel protein M2 into liposomes[4]
  • as a standard sample to define spectral fingerproint using Time-of-flight secondary ion mass spectrometry (ToF-SIMS)[5]
  • to evaluate the contribution of various phospholipids to the formation of foam in the amniotic fluid[6]

Biochem/physiol Actions

Sphingomyelin is the second most abundant lipid and major sphingolipid component of HDL and the plasma membrane. It forms cholesterol-enriched lipid rafts. It has a key role in the availability of plasma membrane-free cholesterol.[7]

Analysis Note

Contains primarily palmitic acid.

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Este artículo
85615CS0001860061P
Egg SM Avanti Research™ - A Croda Brand

Avanti

860061P

Egg SM

assay

≥95%

assay

≥98.0% (TLC)

assay

-

assay

>99% (TLC)

functional group

phospholipid

functional group

phospholipid

functional group

-

functional group

-

biological source

chicken egg yolk

biological source

chicken egg yolk

biological source

-

biological source

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

ambient

shipped in

ambient

shipped in

dry ice

shipped in

dry ice

form

powder

form

powder

form

-

form

powder


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Preguntas

1–2 de 2 Preguntas  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 respuesta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 respuesta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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