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Merck

RES3077T-A7

SAFC

Tricine

Fabricación farmacéutica

Sinónimos:

Tricine, N-[Tris(hydroxymethyl)methyl]glycine

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About This Item

Fórmula lineal:
(HOCH2)3CNHCH2CO2H
Número de CAS:
Peso molecular:
179.17
Beilstein:
1937804
Número CE:
Número MDL:
Código UNSPSC:
12161700
NACRES:
NA.21

origen biológico

synthetic

Nivel de calidad

formulario

powder

técnicas

cell culture | mammalian: suitable

impurezas

Endotoxin, microbial, and trace metals; tested

intervalo de pH útil

7.4-8.8

pKa (25 °C)

8.1

idoneidad

suitable for manufacturing use

actividad extraña

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

cadena SMILES

OCC(CO)(CO)NCC(O)=O

InChI

1S/C6H13NO5/c8-2-6(3-9,4-10)7-1-5(11)12/h7-10H,1-4H2,(H,11,12)

Clave InChI

SEQKRHFRPICQDD-UHFFFAOYSA-N

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Descripción general

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Aplicación

Buffer component for separation of low molecular weight peptides.
Tricine is a biological buffer often referred to as a “Good′s” buffer. The pKa of Tricine is 8.1 which makes Tricine is a good candidate for biological applications that require pH control above physiological. Tricine is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

Tricine can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for electrophoresis, protein purification and diagnostic reagent production.

Envase

Product is available in the following package sizes:
RES3077T-A701X: 100 gm container
RES3077T-A702X: 1 kg container
RES3077T-A704X: 10 kg container
RES3077T-A705X: 25 kg container

Información legal

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

sustituido por

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

13 - Non Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Arpita Gantayet et al.
Biofouling, 29(1), 77-85 (2012-12-06)
The freshwater zebra mussel (Dreissena polymorpha) is a notorious biofouling organism. It adheres to a variety of substrata underwater by means of a proteinaceous structure called the byssus, which consists of a number of threads with adhesive plaques at the
Hermann Schägger
Nature protocols, 1(1), 16-22 (2007-04-05)
Tricine-SDS-PAGE is commonly used to separate proteins in the mass range 1-100 kDa. It is the preferred electrophoretic system for the resolution of proteins smaller than 30 kDa. The concentrations of acrylamide used in the gels are lower than in
Thierry Rabilloud
Journal of proteomics, 73(8), 1562-1572 (2010-04-17)
Electrophoretic separations of proteins are widely used in proteomic analyses, and rely heavily on SDS electrophoresis. This mode of separation is almost exclusively used when a single dimension separation is performed, and generally represents the second dimension of two-dimensional separations.
Christian Nilsson et al.
Electrophoresis, 31(3), 459-464 (2010-02-02)
Totally porous lipid-based liquid crystalline nanoparticles were used as pseudostationary phase for capillary electroseparation with LIF detection of proteins at physiological conditions using unmodified cyclic olefin copolymer capillaries (Topas, 6.7 cm effective length). In the absence of nanoparticles, i.e. in
Bin Deng et al.
PloS one, 9(7), e102362-e102362 (2014-07-19)
Maresins are a new family of anti-inflammatory and pro-resolving lipid mediators biosynthesized from docosahexaenoic acid (DHA) by macrophages. Here we identified a novel pro-resolving product, 13R,14S-dihydroxy-docosahexaenoic acid (13R,14S-diHDHA), produced by human macrophages. PCR mapping of 12-lipoxygenase (12-LOX) mRNA sequence in

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