PRS2221

Anti-BAFF antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-BLyS, Anti-Tall, Anti-Thank, Anti-Tumor necrosis factor (ligand) superfamily, member 13b
• Número MDL: MFCD02265860
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: predicted mol wt 31 kDa
• reactividad de especies: human, rat, mouse
• técnicas: immunocytochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• Nº de acceso UniProt: Q9Y275
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... TNFSF13B(10673)

Descripción

Descripción general

B-lymphocyte activating factor (BAFF/TNFSF13B) is a cytokine that belongs to the TNF (tumor necrosis factor) superfamily. BAFF is located on human chromosome 13q33.

Inmunógeno

a peptide corresponding to amino acids near the carboxy-terminus of human BAFF.

Acciones bioquímicas o fisiológicas

B cell activating factor (BAFF) participates in B cell and T cell mediated immunity. It plays a key role in the survival and differentiation of B cells. Mutations in BAFF regulates the levels of antibody. BAFF also participates in enhancing the responses of IL-6 (interlukin-6) and TNF-α (tumor necrosis factor alpha), that helps hepatocytes in the production of acute-phase protein.

Ligadura / enlace

The action of this antibody can be blocked using blocking peptide SBP2221.

Forma física

Solution in phosphate buffered saline containing 0.02% sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable