PLA0172

Rabbit anti-PML Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Sinónimos: MYL, PML/RARA fusion, PP8675, RING finger protein 71, RNF71, TRIM19, inducer of, probable transcription factor PML, promyelocytic leukemia, promyelocytic leukemia protein, tripartite motif protein TRIM19, tripartite motif-containing protein 19
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• grado: Powered by Bethyl Laboratories, Inc.
• reactividad de especies: human
• técnicas: immunohistochemistry: 1:200- 1:1,000; immunoprecipitation (IP): 2-5 μg/mg; western blot: 1:2,000- 1:10,000
• nº de acceso: NP_150241.2
• Nº de acceso UniProt: P29590
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: rabbit ... PML(5371)

Descripción

Inmunógeno

The epitope recognized by PLA0172 maps to a region between residue 375 and 425 of promyelocytic leukemia using the numbering given in entry NP_150241.2 (GeneID 5371).

Forma física

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Otras notas

PML is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. PML is a multifunctional protein involved in activities such as tumor growth suppression, hematopoietic differentiation, gene transcription, apoptotic induction, and viral immunity. PML is often involved in chromosomal translocations with the retinoic acid receptor alpha gene. PML-retinoic acid receptor translocations are associated with acute promyelocytic leukemia.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable