P9122
Anti-Purinergic Receptor P2X7 (extracellular) antibody produced in rabbit
affinity isolated antibody, lyophilized powder
Sinónimos:
Anti-P2Z
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Productos recomendados
origen biológico
rabbit
Nivel de calidad
conjugado
unconjugated
forma del anticuerpo
affinity isolated antibody
tipo de anticuerpo
primary antibodies
clon
polyclonal
formulario
lyophilized powder
reactividad de especies
human, rat, mouse
técnicas
western blot: 1:200 using rat brain lysate and human cell lines
Nº de acceso UniProt
Condiciones de envío
dry ice
temp. de almacenamiento
−20°C
modificación del objetivo postraduccional
unmodified
Información sobre el gen
human ... P2RX7(5027)
mouse ... P2rx7(18439)
rat ... P2rx7(29665)
Descripción general
P2X receptors are membrane-bound ion channels that are activated by extracellular ATP. These receptors consist of seven known isoforms ranging from P2X1 to P2X7 . P2X7 modulates several cellular functions such as cell death, cytokine release and mRNA synthesis . Anti-Purinergic Receptor P2(X7) (extracellular) antibody is specific for P2X7 in rats and mice. The antibody also reacts with human K562 (Chronic myelogeneous leukemia); WEHI-231 (Lymphoma, B lymphocyte) and HL-60 (promyelocytic leukemia) cell lines.
Inmunógeno
Synthetic peptide corresponding to residues 136-152 of mouse P2X7 receptor. This antigenic epitope is identical in humans and rats; whereas in bovines, only 14/17 residues are identical.
Aplicación
Anti-Purinergic Receptor P2(X7) (extracellular) antibody is suitable for use in immunoblot and western blot (1:200, using rat brain lysate and human cell lines).
Forma física
Lyophilized from phosphate buffered saline, pH 7.4, 1% BSA, and 0.05% sodium azide.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
¿No encuentra el producto adecuado?
Pruebe nuestro Herramienta de selección de productos.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Y Ding et al.
Journal of the autonomic nervous system, 81(1-3), 289-294 (2000-06-28)
A role for ATP in nociception and pain induction was proposed on the basis of human psychophysical experiments shortly after the formulation of the purinergic hypothesis. Following the pharmacological definition of distinct P2X and P2Y purinergic receptor subtypes by Burnstock
Audrey Cambon et al.
Frontiers in immunology, 14, 1228122-1228122 (2023-12-11)
IL-1β is a leaderless cytokine with poorly known secretory mechanisms that is barely detectable in serum of patients, including those with an IL-1β-mediated disease such as systemic juvenile idiopathic arthritis (sJIA). Leukocyte microvesicles (MVs) may be a mechanism of IL-1β
Molecular Physiology of P2X Receptors.
North, R., A.
Physical Review, 82(4), 1013-1067 (2002)
Letizia Penolazzi et al.
Frontiers in cell and developmental biology, 11, 1180774-1180774 (2023-05-22)
Identifying the subcellular localization of a protein within a cell is often an essential step in understanding its function. The main objective of this report was to determine the presence of the P2X7 receptor (P2X7R) in healthy human cells of
Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance.
Alba Clara Sarti et al.
Function (Oxford, England), 2(2), zqab005-zqab005 (2021-01-28)
Basal expression of the P2X7 receptor (P2X7R) improves mitochondrial metabolism, Adenosine 5'-triphosphate (ATP) synthesis, and overall fitness of immune and non-immune cells. We investigated P2X7R contribution to energy metabolism and subcellular localization in fibroblasts (mouse embryo fibroblasts and HEK293 human
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico