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P7936

Sigma-Aldrich

Phosphocreatine disodium salt hydrate

≥97%

Sinónimos:

Creatine phosphate disodium salt, N-(Imino[phosphonoamino]methyl)-N-methylglycine

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About This Item

Fórmula lineal:
C4H8N3O5PNa2 · x H2O
Número de CAS:
19333-65-4
Peso molecular:
255.08 (anhydrous basis)
Número CE:
213-074-6
Número MDL:
MFCD00150191
Código UNSPSC:
12352204
ID de la sustancia en PubChem:
24898895
NACRES:
NA.32

product name

Phosphocreatine disodium salt hydrate, ≥97%

Análisis

≥97%

formulario

powder

impurezas

≤0.02% free creatine

color

white

solubilidad

water: 50 mg/mL, clear, colorless

temp. de almacenamiento

−20°C

cadena SMILES

O.[Na+].[Na+].CN(CC(O)=O)C(=N)NP([O-])([O-])=O

InChI

1S/C4H10N3O5P.2Na.H2O/c1-7(2-3(8)9)4(5)6-13(10,11)12;;;/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12);;;1H2/q;2*+1;/p-2

Clave InChI

KZVYPOKBYRXZKS-UHFFFAOYSA-L

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Aplicación

Phosphocreatine disodium salt hydrate has been used:
  • as a component: of Xenopus buffer (XB) buffer to remove the membrane-bound proteins
  • of M5+ buffer to perform polarized total internal reflection fluorescence (polTIRF) experiments
  • of ATP regenerating system for 7-nitro-2-1,3-benzoxadiazol-4-yl phospholipid(NBD-PL) translocation assay

Acciones bioquímicas o fisiológicas

Phosphocreatine disodium salt hydrate is useful to study nasopharyngeal carcinoma cells and induced temporary cardiac arrest. It also evaluate the effects of adenosine A(2A) receptor modulation in the nucleus accumbens on cocaine seeking in rats.
Phosphocreatine is widely known for its quickest form of regeneration using enzyme creatine kinase. It functions as a temporal energy buffer. Phosphocreatine is present in muscle tissues and plays a major role in maintaining energy homeostasis in muscle cells.
Phosphocreatine, a high-energy phosphate reservoir in vertebrate and some invertebrate muscles, provides phosphate for ADP-ATP conversion.

Nota de preparación

Prepared enzymatically

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Casey E O'Neill et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 37(5), 1245-1256 (2011-12-16)
Repeated cocaine administration enhances dopamine D(2) receptor sensitivity in the mesolimbic dopamine system, which contributes to drug relapse. Adenosine A(2A) receptors are colocalized with D(2) receptors on nucleus accumbens (NAc) medium spiny neurons where they antagonize D(2) receptor activity. Thus
Protective effects of a magnesium magnetic isotope (Mg(25) )-exchanging nanoparticle ((25) MgPMC(16) ) on mitochondrial functional disorders in esmolol-induced cardiac arrest in rats
Adeli, S., et al.
Auton. Autocoid Pharmacol., 32, 1-7 (2012)
John F Beausang et al.
Biophysical journal, 104(6), 1263-1273 (2013-03-27)
Myosin V is biomolecular motor with two actin-binding domains (heads) that take multiple steps along actin by a hand-over-hand mechanism. We used high-speed polarized total internal reflection fluorescence (polTIRF) microscopy to study the structural dynamics of single myosin V molecules
Cyril Bernis et al.
Methods in cell biology, 122, 165-191 (2014-05-27)
The large and complex eukaryotic nucleus is the arbiter of DNA replication, RNA transcription, splicing, and ribosome assembly. With the advent of in vitro nuclear reconstitution extracts derived from Xenopus eggs in the 1980s, it became possible to assemble multiple
Lucas Guimarães-Ferreira
Einstein (Sao Paulo, Brazil), 12(1), 126-131 (2014-04-15)
Adenosine triphosphate is the present energy currency in the body, and is used in various cellular and indispensable processes for the maintenance of cell homeostasis. The regeneration mechanisms of adenosine triphosphate, from the product of its hydrolysis - adenosine diphosphate
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