This product is lyophilized from mouse ascites fluid. The total protein content is verified prior to lyophilization. The 15 mg/mL value is the pre-lyophilization total protein content. The Myeloma Protein-Densitometry is performed after lyophilization when reconstituted to 1ml in water. The 5 mg value is specific to the Myeloma Protein (IgG1 kappa) only.
M7894
IgG1, Kappa from murine myeloma
clone MOPC 21, ascites fluid, lyophilized powder
Sinónimos:
Mouse IgG1-κ
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| A ustedes/SKU | Disponibilidad | Precio |
|---|---|---|
5 mg | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 375,00 € |
Acerca de este artículo
Conjugate:
unconjugated
Clone:
MOPC 21, monoclonal
Application:
—
Citations:
39
375,00 €
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Servicio técnico
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Permítanos ayudarlebiological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
ascites fluid
clone
MOPC 21, monoclonal
form
lyophilized powder
application(s)
research pathology
storage temp.
2-8°C
target post-translational modification
unmodified
General description
The MOPC-21 tumor line that produces mouse IgG1, κ is a mineral oil induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. Immunoglobulins G are made up of two identical light chains and two identical heavy chains, that are covalently connected by interchain disulphide bonds. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b, IgG2c and IgG3.
Application
IgG1, Kappa from murine myeloma has been used:
- in stimulation assay and enzyme-linked immunosorbent assay (ELISA)
- as isotype controls in islet hormone production
- in flow cytometric analysis, in cell migration assay
- as control antibody in evaluation of methylation
Biochem/physiol Actions
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.[1]
Preparation Note
Reconstitute with 1 mL deionized water.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
1 of 1
Este artículo | |||
|---|---|---|---|
| clone MOPC 21, monoclonal | clone MOPC 31C, monoclonal | clone DX, monoclonal | clone TEPC 183, monoclonal |
| biological source mouse | biological source mouse | biological source mouse | biological source mouse |
| antibody form ascites fluid | antibody form ascites fluid | antibody form purified immunoglobulin | antibody form purified immunoglobulin |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 300 |
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Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Good morning, I have a question about product specification. Looks like 1vial contains about 5mg and the protein, correct? What does the 15mg/ml protein by Biuret info mean? Because if the reconstitution is done in 1mL, the highest conc. is 5mg/mL, no? Ty
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